Glenn J Lesser Selected Research

Hypoxia (Hypoxemia)

1/2020	Attenuating hypoxia driven malignant behavior in glioblastoma with a novel hypoxia-inducible factor 2 alpha inhibitor.
1/2018	Hypoxia-inducible factor 2α: a novel target in gliomas.

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Glenn J Lesser Research Topics

Disease

35	Neoplasms (Cancer) 05/2024 - 01/2004
19	Glioblastoma (Glioblastoma Multiforme) 01/2024 - 01/2004
18	Breast Neoplasms (Breast Cancer) 05/2024 - 11/2006
18	Glioma (Gliomas) 01/2024 - 01/2004
17	Brain Neoplasms (Brain Tumor) 03/2021 - 01/2004
5	Cognitive Dysfunction 05/2024 - 12/2014
5	Lymphoma (Lymphomas) 04/2024 - 09/2004
4	Head and Neck Neoplasms (Head and Neck Cancer) 05/2024 - 01/2018
4	Fatigue 02/2019 - 03/2013
3	Disease Progression 07/2023 - 10/2010
3	Thrombocytopenia (Thrombopenia) 01/2018 - 12/2004
3	Lung Neoplasms (Lung Cancer) 01/2016 - 11/2006
2	Hypertension (High Blood Pressure) 04/2024 - 01/2017
2	Neoplasm Metastasis (Metastasis) 07/2023 - 10/2021
2	Hyperglycemia 07/2023 - 01/2018
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 10/2021 - 02/2008
2	Hypoxia (Hypoxemia) 01/2020 - 01/2018
2	Chronic Disease (Chronic Diseases) 10/2015 - 03/2013
2	Astrocytoma (Pilocytic Astrocytoma) 05/2015 - 02/2008
2	Intracranial Hemorrhages (Intracranial Hemorrhage) 12/2012 - 12/2004
2	Vitelliform Macular Dystrophy 08/2009 - 11/2005
1	Xerostomia 05/2024
1	Ulcer 01/2024
1	Craniopharyngioma (Craniopharyngiomas) 07/2023
1	Necrosis 10/2022
1	Inflammation (Inflammations) 09/2022
1	Basal Cell Nevus Syndrome (Gorlin Syndrome) 09/2022
1	Microsatellite Instability 10/2021
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 03/2021
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2020
1	Residual Neoplasm 10/2019

Drug/Important Bio-Agent (IBA)

16	Temozolomide (Temodar)FDA LinkGeneric 11/2023 - 02/2008
7	Biomarkers (Surrogate Marker)IBA 04/2024 - 12/2017
4	Bevacizumab (Avastin)FDA Link 10/2022 - 01/2015
3	Atorvastatin (Lipitor)FDA Link 04/2024 - 09/2022
2	Donepezil (Aricept)FDA LinkGeneric 05/2024 - 01/2019
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2024 - 09/2022
2	RNA (Ribonucleic Acid)IBA 07/2023 - 01/2018
2	Proteins (Proteins, Gene)FDA Link 07/2023 - 06/2015
2	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2023 - 09/2022
2	LactoferrinIBA 03/2022 - 09/2018
2	theasinensin AIBA 03/2022 - 09/2018
2	ErbB Receptors (EGF Receptor)IBA 06/2020 - 02/2008
2	PT2385IBA 01/2020 - 01/2018
2	VaccinesIBA 10/2019 - 02/2008
2	Influenza Vaccines (Influenza Vaccine)FDA Link 08/2018 - 12/2014
2	Transcription Factors (Transcription Factor)IBA 01/2018 - 01/2018
2	Vitamin E FDA LinkGeneric 01/2018 - 03/2013
2	Vorinostat FDA Link 01/2018 - 06/2015
2	coenzyme Q10 (CoQ10)IBA 01/2018 - 03/2013
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2018 - 01/2017
2	Tyrosine Kinase InhibitorsIBA 01/2017 - 02/2008
2	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 12/2012 - 12/2004
1	Nootropic Agents (Nootropics)IBA 05/2024
1	salicylhydroxamic acid (SHAM)IBA 05/2024
1	Antihypertensive Agents (Antihypertensives)IBA 04/2024
1	AnthracyclinesIBA 04/2024
1	GossypolIBA 01/2024
1	gossypol acetic acidIBA 01/2024
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 11/2023
1	veliparibIBA 11/2023
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 11/2023
1	Membrane Proteins (Integral Membrane Proteins)IBA 07/2023
1	AntibodiesIBA 07/2023
1	cobimetinibIBA 07/2023
1	Creatine Kinase (Creatine Phosphokinase)IBA 07/2023
1	VemurafenibIBA 07/2023
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 07/2023
1	HhAntag691IBA 09/2022
1	Antineoplastic Agents (Antineoplastics)IBA 10/2021
1	B7-H1 AntigenIBA 10/2021
1	Peptides (Polypeptides)IBA 10/2021
1	Immune Checkpoint InhibitorsIBA 10/2021
1	APOBEC-1 DeaminaseIBA 10/2021
1	pembrolizumabIBA 10/2021
1	atezolizumabIBA 10/2021
1	Topotecan (Hycamtin)FDA LinkGeneric 03/2021
1	Topoisomerase InhibitorsIBA 03/2021
1	2,2- dimethyl- N- (6- oxo- 6,7- dihydro- 5H- dibenzo(b,d)azepin- 7- yl)- N'- (2,2,3,3,3- pentafluoropropyl)malonamideIBA 01/2021
1	EnzymesIBA 01/2021
1	epidermal growth factor receptor VIIIIBA 06/2020
1	osimertinibIBA 06/2020
1	endothelial PAS domain-containing protein 1IBA 01/2020
1	taxaneIBA 01/2020

Therapy/Procedure

25	Therapeutics 05/2024 - 01/2004
25	Radiotherapy 05/2024 - 01/2004
12	Drug Therapy (Chemotherapy) 04/2024 - 08/2009
3	Adjuvant Chemotherapy 05/2024 - 03/2013
3	Aftercare (After-Treatment) 10/2023 - 03/2017
2	Immunotherapy 07/2023 - 12/2017
2	Salvage Therapy 05/2015 - 11/2005
2	Perioperative Period 12/2012 - 12/2004
2	Contraindications 12/2012 - 12/2004
1	Oral Hygiene (Dental Hygiene) 05/2024
1	Segmental Mastectomy (Lumpectomy) 12/2022
1	Mastectomy (Mammectomy) 12/2022
1	Re-Irradiation 10/2022
1	Computer-Assisted Surgery (Image Guided Surgery) 03/2020
1	Medical Day Care (Partial Hospitalization) 03/2020
1	Chemoradiotherapy 01/2020